Characterizing the Mechanism of Action of Essential Oils on Skin Homeostasis—Data from Sonographic Imaging, Epidermal Water Dynamics, and Skin Biomechanics

Essential oils (EOs) have been recognized as materials of interest for dermatological applications, although some doubts remain regarding their safety and efficacy. We studied the action mechanisms EOs from lavender sage in human skin. Extracted were incorporated (at 5% 10%) almond oil a vehicle. Eleven healthy volunteers selected prepared tested on both forearms. All procedures respected principles good clinical practice. Effects followed through high resolution sonography (HRS), epidermal water dynamics, biomechanics. variables measured before 30 min after application. Nonparametric statistical comparisons applied (p < 0.05). HRS revealed more echogenic epidermis, with significant echogenicity decrease dermis (higher retention) all formulations. Significant TEWL an increase superficial deep hydration also observed. These results indicate that penetrate only into most layers skin, which is important profile. Furthermore, this “filmogenic” mechanism improving balance seems to connect directly observed biomechanical enhancement. confirm relevance these compounds, particular restore content prevent xerosis other related disorders sensitive (atopic, elderly) patients.